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Sizhuang He

Second-Year Ph.D. Student in Computer Science
Yale University
sizhuang.he (at) yale.edu

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Curriculum Vitae

Last updated: October 09, 2025.

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Research Interest

Generative Modeling: Flow Matching, Diffusion, Discrete Diffusion, Operator Learning: Modeling Continuous Spatiotemporal Dynamics, Integral Equations, Computational Biology: Single-cell Transcriptomics Data Analysis, LLMs and Agentic AI: Autonomous Systems for Biological Discovery

Education

Yale University New Haven, CT
Ph.D. in Computer Science Aug. 2024 -- Present
  • Advisor: Dr. David van Dijk
  • Research Focus: Machine Learning for Computational Biology
University of Michigan, Ann Arbor Ann Arbor, MI
Bachelor of Science in Honors Mathematics (Minor in Computer Science) Sep. 2019 -- May 2023
  • Graduated with Highest Distinction
  • GPA: 4.0 / 4.0

Publications

  1. Non-Markovian Discrete Diffusion with Causal Language Models
    Y. Zhang*, S. He*, et al.
    NeurIPS 2025 (Poster)
  2. TANTE: Time-Adaptive Operator Learning via Neural Taylor Expansion
    Z. Wu, S. Wang, S. Zhang, S. He, et al.
    In Review
  3. Intelligence at the Edge of Chaos
    S. Zhang*, A. Patel*, S. Rizvi, N. Liu, S. He, et al.
    ICLR 2025 (Poster)
  4. COAST: Intelligent Time-Adaptive Neural Operators
    Z. Wu, S. Zhang, S. He, et al.
    AI4MATH Workshop at ICML 2025 (Poster)
  5. Scaling Large Language Models for Next-Generation Single-Cell Analysis
    S. Rizvi*, D. Levine*, A. Patel*, S. Zhang*, E. Wang*, S. He, et al.
    bioRxiv
  6. CaLMFlow: Flow Matching using Causal Language Models
    S. He*, D. Levine*, et al.
    arXiv
  7. Operator Learning Meets Numerical Analysis: Improving Neural Networks through Iterative Methods
    E. Zappala, D. Levine, S. He, et al.
    arXiv

* denotes equal contribution.

Honors & Awards

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